Scientist (f/m/d) Product Design & Formulation

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Design. Progress. Together.

CureVac AG is a global biopharmaceutical company researching and developing novel drugs based on the natural molecule Messenger RNA (mRNA). Our focus is on prophylactic vaccines, innovative cancer immunotherapies and protein-based therapies. Currently all RNA people are striving to achieve our main goal: To bring multiple best-in-class mRNA drugs to market.
To strengthen our team in Tübingen near Stuttgart, we are currently looking to recruit a

Scientist (f/m/d) Product Design & Formulation
Job-ID: 3702-2101

Your responsibilities:

We are seeking for Formulation Scientists eager to to join our department Product Design and Formulation in Tübingen, Germany.  As a Formulation Scientist, you will be responsible for the development and evaluation of novel mRNA delivery systems within our discovery programs, supporting of pharmacology and toxicology studies utilizing in vitro and in vivo models, formulation process development and troubleshooting as well as technology transfer to internal and external teams.

As Formulation Scientist your responsibilities include, but are not limited to:
  • Independently design, develop and organize scientific experiments in the area of innovative mRNA delivery systems and optimization of existing drug delivery formulations (e.g. interpret results, evaluate data, write and review reports)
  • Contribution to develop and implement new technologies or strategies within the team to solve drug delivery challenges (e.g. communicate/interpret and present results, evaluate data, write and review reports)
  • Analytical characterization and optimization studies (excipient screening, stability, and shelf-life determination)
  • Supporting transfer and scale-up of manufacturing processes to GMP production
  • Design of animal studies for PK/PD, efficacy and safety assessment of novel formulations
  • Communicate and interact with different departments across the corporate, external project partners and clients to facilitate transfer of knowledge
  • Technology scouting and evaluation, patent and literature search as well as scientific and business writing

Your qualifications:

  • Ph.D. in Pharmacy/Pharmaceutical Sciences, Chemistry, biochemistry, biomedical engineering or related fields with some years of post-graduate laboratory experience in nanoparticle formulation development, nucleic acid therapeutics, or drug delivery
  • Industrial experience in formulation development and scale-up manufacturing of nanoparticle-based modalities is an asset
  • Knowledge of nano-sized pharmaceutical formulations,  and requirements for their parenteral and local application. Knowledge of standard methods for LNP preparation and characterization is highly desirable
  • Expertise in physicochemical or structural characterization of lipid and polymer-based nanoparticle preparations (e.g. DLS, gel electrophoresis, HPLC). Insights into advanced characterization techniques such as Cryo-TEM, SAXS, CD, AF4 is a plus
  • Experience in providing formulation expertise and insights to interdisciplinary teams during preclinical development. Hands on experience in conducting cell-based assays as well as in vivo PK/PD and efficacy studies for formulation screening is a plus
  • Cultivate a scientific mind-set, dedicated commitment, flexibility, creativity and team spirit
  • Fluency in oral and written English is essential with the ability to work with state-of the art software tools

With much passion and sense of responsibility, we work together on the medical revolution. We pride ourselves on maintaining an honest and trusting relationship with each other which is characterized by openness to new ideas and continuous progress. Mutual respect, reliability and personal initiative are self-evident for us.

Design your future with us – become part of the RNA people!   

We look forward to receiving your application via our CareerPortal.

CureVac AG

Human Resources
Ms Christina Glass
Friedrich-Miescher-Straße 15
72076 Tübingen